Computational Biologist (Immunology) Job at Astrix, South San Francisco, CA

V1pZa2tvMEZMTTFZTER4b0x4c0Q4WHh4dXc9PQ==
  • Astrix
  • South San Francisco, CA

Job Description

We’re seeking a mission-driven Computational Biologist to help reshape how we discover and develop therapies for IBD. In this role, you’ll work at the intersection of immunology, machine learning, and multimodal data integration, applying cutting-edge tools to uncover new therapeutic targets and biomarkers.

Location: Onsite in South San Francisco, CA (No remote option)

Duration: 6 month contract with strong potential for extension

Pay rate: $38- $50/ hr. DOE

Team: Bioinformatics – Computational Biology & Translation

Project Objective:

Design, implement, and sustain a computational framework for integrating multimodal datasets—spanning molecular, cellular, clinical, and imaging data—to drive target and biomarker discovery in IBD.

Key Responsibilities:

  • Integrate and analyze multimodal data (e.g. scRNA-seq, spatial transcriptomics, proteomics, histology, endoscopy videos)
  • Build generalized pipelines for target review and biomarker identification
  • Incorporate AI/ML and foundation models into data analysis
  • Translate data findings into target and biomarker recommendations
  • Present findings to multidisciplinary teams and help guide R&D decisions

Requirements:

  • PhD in Computational Biology, Bioinformatics, or a related discipline with 3–5 years of relevant experience in academia (postdoctoral) or industry settings
  • Strong background in immunology, with a preference for expertise in IBD pathogenesis and current therapeutic strategies
  • Proven experience in analyzing complex biological datasets, including multimodal omics and clinical data
  • Proficiency in applying AI/ML approaches, including the use and fine-tuning of foundation models for biological and clinical data interpretation
  • Solid programming skills in Python and/or R, with familiarity in developing and maintaining computational pipelines
  • Hands-on experience with bioinformatics tools such as Seurat, Scanpy, Cell Ranger, Squidpy, or similar platforms
  • Understanding of spatial omics and single-cell analysis methods
  • Knowledge of bioinformatics data standards and best practices for data integration
  • Excellent communication and collaboration skills, with the ability to work effectively in cross-functional teams and convey complex computational insights to diverse stakeholders

#INDBH

#LI-DNP

Job Tags

Contract work, Remote job,

Similar Jobs

Toshiba Global Commerce Solutions

Senior software architect Job at Toshiba Global Commerce Solutions

 ...use of the self-checkout at Lowe's Foods, earned fuel rewards at Kroger, or just paid for purchases at retailers such as Walmart, Michaels, Carrefour, The Gap, Calvin Klein, Boots, Cencosud, BJ's, or Costco? These are just a few examples of our in-store solutions and impressive... 

Orlando Health

Accounts Payable Specialist I Job at Orlando Health

Accounts Payable Specialist I Location Orlando, FL (South Orange area) : Position Summary: Orlando Health is seeking an Account Payable Specialist I . This role will process vendor invoices (electronic and paper) in various systems with attention to detail, reasonableness... 

LSG Sky Chefs

Food Production Manager - Airline Catering Job at LSG Sky Chefs

 ...Job Title: Food Production Manager - Airline Catering Job Location: Boston-USA-02128 Work Location Type: On-Site Salary Range: $102,000.00 - 130,000.00 About us LSG Sky Chefs is one of the worlds largest airline catering and hospitality... 

ManorCare Health Services-Summer Trace

Travel Occupational Therapist - Paying up to $2,398/week Job at ManorCare Health Services-Summer Trace

We are seeking a dedicated Travel Occupational Therapist to join our team in Portsmouth, VA. Responsibilities Include Assessing and developing individualized treatment plans for patients with diverse needs. Implementing therapeutic interventions to improve patients... 

Toll Brothers

Purchasing Manager Job at Toll Brothers

 ...an exceptional place to work that is inclusive to all. Toll Brothers , America's Leading Luxury Home Builder, is seeking a Purchasing Manager for our office in Greenwood Village, Colorado. What is the opportunity? This position is on-site 5 days per...